Anti-MTMR14抗體,肌管素相關蛋白14抗體*優品產品詳細資料

產品編號 BYK-11217R

英文名稱 MTMR14
中文名稱 肌管素相關蛋白14抗體
別    名 C3orf29; Egg derived tyrosine phosphatase homolog; FLJ11546; FLJ22405; FLJ46453; FLJ90311; HCV NS5A transactivated protein 4 splice variant A binding protein 1; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; hJumpy; jumpy; MTMR 14; MTMR14; MTMR-14; MTMRE_HUMAN; Myotubularin related protein 14; Myotubularin-related protein 14; NS5ATP4ABP1.
研究領域 細胞生物  免疫學  激酶和磷酸酶  
分 子 量 72kDa
細胞定位 細胞漿 細胞膜 

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產品應用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產品應用不做依據，具體產品應用與實驗稀釋比請！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-MTMR14抗體,肌管素相關蛋白14抗體*優品產品介紹 

      Myotubularin-related protein 14 (MTMR14), also known as Jumpy, is a myotubularin-related phosphoinositol-3-phosphate (PI3P) phosphatase (1). Mutations in the MTMR14 gene have been associated with centronuclear myopathy (1). MTMR14 deficiency in mice leads to altered calcium homeostasis and muscle disorders (2). MTMR14 has also been shown to play a role in autophagy, a process that is highly regulated by phosphatidylinositides through the type III PI3K, Vps34 (3). MTMR14 was localized to autophagic isolation membranes and early autophagosomes (3). In these studies, MTMR14 inhibited autophagy and mutations of MTMR14 associated with centronuclear myopathy were also defective in autophagy inhibition. In zebrafish, MTMR14 knockdown was shown to increase the number of autophagosomes, suggesting that its activity is associated with an inhibition of autophagy (4).

 此相關標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記 

     相關產品：

     Anti-GSTA3抗體,*S轉移酶A3抗體

Anti-phospho-GADD153(Ser30),磷酸化GADD153抗體
Anti-phospho-GIT1(Tyr545),磷酸化G蛋白偶聯受體激酶相互作用蛋白1抗體
Anti-phospho-GFAP(Ser8),磷酸化膠質纖維酸性蛋白抗體
Anti-phospho-GABBR2(Ser783),磷酸化G氨基丁酸B型受體2抗體
Anti-phospho-Gria2(Ser880),磷酸化*受體2抗體
Anti-G protein alpha 12抗體,鳥苷酸調節蛋白12抗體
Anti-phospho-GNA12(Ser68),磷酸化鳥苷酸調節蛋白12抗體
Anti-phospho-GSK-3 Beta(Ser21),磷酸化糖原合酶激酶3β抗體
Anti-GIT1抗體,G蛋白偶聯受體激酶相互作用蛋白1抗體
Anti-phospho-GIT1(Ser375),磷酸化G蛋白偶聯受體激酶相互作用蛋白1抗體
Anti-phospho-GATA6(Tyr271),磷酸化GATA結合蛋白6抗體
Anti-G3BP1抗體,Ras GTP酶活化蛋白結合蛋白1抗體
Anti-GJB3抗體,間隙連接蛋白31抗體
Anti-GPI抗體,糖磷脂酰肌醇抗體
Anti-Glutamine synthetase抗體,*合成酶/*氨連接酶抗體
Anti-GOLPH2抗體,高爾基體膜蛋白GP73抗體
Anti-GIRK2抗體,G蛋白激活內流鉀通道蛋白2抗體
Anti-GPR39抗體,G蛋白偶聯受體39抗體
Anti-GLUT8抗體,葡萄糖轉運蛋白8抗體
Anti-Growth Arrest Specific Protein 7抗體,生長休止特定蛋白7抗體