Anti-Reprimo抗體,細(xì)胞質(zhì)內(nèi)的糖基化蛋白抗體產(chǎn)品詳細(xì)資料

產(chǎn)品編號(hào) BYK-1885R

英文名稱 Reprimo
中文名稱 細(xì)胞質(zhì)內(nèi)的糖基化蛋白抗體
別    名 Protein reprimo.; reprimo, TP53 dependent G2 arrest mediator candidate; 2410012A13RIK; FLJ90327; MGC109515; REPRIMO; RPRM; RPRM_HUMAN.
研究領(lǐng)域 腫瘤  細(xì)胞生物  細(xì)胞凋亡  細(xì)胞周期蛋白  糖蛋白  
分 子 量 12kDa

抗體來(lái)源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應(yīng)用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應(yīng)用不做依據(jù)，具體產(chǎn)品應(yīng)用與實(shí)驗(yàn)稀釋比請(qǐng)！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-Reprimo抗體,細(xì)胞質(zhì)內(nèi)的糖基化蛋白抗體產(chǎn)品介紹 

      Reprimo, also known as TP53 dependent G2 arrest mediator candidate or RPRM, is a 109 amino acid cytoplasmic protein belonging to the Reprimo family, which is involved in the regulation of p53-dependent G2 arrest of the cell cycle. Reprimo may initiate cell cycle arrest by inhibiting CDC2 and nuclear translocation of the CDC2 cyclin B1 complex. A highly glycosylated protein, Reprimo also plays a role in cell cycle surveillance and DNA repair. Hypermethylation of Reprimo can lead to its transcriptional repression, which may increase pathogenesis of some types of human cancers. Reprimo has been identified as a potential biomarker for early detection multiple cancers. The gene encoding Reprimo maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome.

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