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Anti-IFI78/MX1抗體,干擾素誘導蛋白P78抗體

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     Anti-IFI78/MX1抗體,干擾素誘導蛋白P78抗體產品詳細資料

產品編號 BYK-10061R

英文名稱 MX1 + MX2
中文名稱 干擾素誘導蛋白P78抗體
別    名 IFI78; N-terminally processed; Human interferon regulated resistance GTP binding protein MXA; IFI 78; IFI 78K; IFI-78K; IFI78; IFI78K; Interferon induced GTP binding protein Mx1; Interferon induced protein p78; Interferon inducible protein p78; Interferon regulated resistance GTP binding protein; Interferon regulated resistance GTP binding protein MxA; Interferon-induced GTP-binding protein Mx1; Interferon-induced protein p78; Interferon-regulated resistance GTP-binding protein MxA; MX 1; MX; MX1; MX1_HUMAN; MxA; Myxoma resistance protein 1; Myxovirus (influenza virus) resistance 1 interferon inducible; Myxovirus (influenza virus) resistance 1 interferon inducible protein p78; Myxovirus (influenza) resistance 1 homolog of murine; Myxovirus resistance protein 1; Interferon induced GTP binding protein Mx2; Interferon regulated resistance GTP binding protein MXB; Interferon-induced GTP-binding protein Mx2 antibody Interferon-regulated resistance GTP-binding protein MxB; MX 2; Mx2; MX2_HUMAN; MXB; Myxovirus (influenza virus) resistance 2; Myxovirus resistance 2; Myxovirus resistance protein 2; p78 related protein; p78-related protein; Second interferon induced protein p78.
研究領域 免疫學  
分 子 量 73/79kDa
細胞定位 細胞漿 

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產品應用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 產品應用不做依據,具體產品應用與實驗稀釋比請!

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-IFI78/MX1抗體,干擾素誘導蛋白P78抗體產品介紹 


      The Dynamin family of microtubule-associated proteins function as GTPases that are involved in microtubule bundling and endocytosis. In mice, Mx2 (myxovirus resistance protein 2) and Mx1 (myxovirus resistance protein 1) are members of the Dynamin family that are involved in the immune response to viral infections. Localized to the cytoplasm, Mx2 contains one GED domain and is expressed in response to viral infection or treatment by IFN-alpha/IFN-beta. Once expression is induced, Mx2 accumulates in the cytoplasm and inhibits the replication of vesicular stomatitis virus (VSV), thereby conferring resistance to VSV infection. Unlike Mx2, Mx1 is localized to the nucleus where, upon induction by IFN-alpha/IFN-beta, it provides selective resistance to infection by the highly lethal H5N1 influenza virus. In humans, MxA and MxB function in a similar manner to Mx1 and Mx2, conferring resistance to specific target viruses. Mx3 is a rat-specific member of the myxovirus resistance protein family.

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