Anti-UBE3A抗體,人乳頭狀瘤病毒E6相關蛋白抗體說明書產品詳細資料

產品編號 BYK-11776R

英文名稱 UBE3A
中文名稱 人乳頭狀瘤病毒E6相關蛋白抗體
別    名 ANCR; Angelman syndrome; AS; CTCL tumor antigen se37 2; E6 AP; E6-AP; E6AP antibody E6AP ubiquitin protein ligase; E6AP ubiquitin protein ligase; E6AP ubiquitin-protein ligase; EPVE6AP; HPVE6A; Human papilloma virus E6 associated protein Angelman syndrome; Human papilloma virus E6 associated protein; Human papillomavirus E6-associated protein; NY REN 54 antigen; NY REN 54 antigen; Oncogenic protein associated protein E6 AP; Oncogenic protein associated protein E6AP; Oncogenic protein-associated protein E6-AP; Renal carcinoma antigen NY REN 54; Renal carcinoma antigen NY-REN-54; UBE 3A; Ube3a; UBE3A protein; UBE3A_HUMAN; Ubiquitin protein ligase E3A; Ubiquitin-protein ligase E3A.
研究領域 腫瘤  細胞生物  染色質和核信號  神經生物學  信號轉導  細胞周期蛋白  表觀遺傳學  泛素                 

抗體來源 Mouse or Rabbit

克隆類型 Monoclonal or Polyclonal
產品應用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產品應用不做依據，具體產品應用與實驗稀釋比請！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-UBE3A抗體,人乳頭狀瘤病毒E6相關蛋白抗體說明書產品介紹： 

      E6-associating protein is a component of the ubiquitin-mediated proteolytic pathway, which selectively targets proteins for degradation by the 26S proteasome. Ubiquitin (Ub) is directly conjugated to protein substrates by the transfer of Ub from an E2 ubiquitin conjugating enzyme to the target protein. This conjugation is facilitated by the enzymatic activity of E3 ubiquitin ligase family members such as E6-AP. Several substrates of E6-AP have been identified and include the tumor suppressor protein p53 and the mammalian homolog of Rad23, HHR23A. Previous studies have indicated that E6-AP associates with the human papillomavirus E6 oncogene, which complexes with p53 and thereby potentiates E6-AP mediated ubiquitination of p53. Genetic mutations that impair E6-AP activity result in the accumulation of p53 in the cytoplasm, and, in many instances, these mutations are associated with the development of the rare neurodevelopmental disorder Angelman syndrome (AS), which is characterized by severe motor dysfunction and mental retardation.

 此相關標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記 

    相關產品：

     Anti-HSD3a抗體,羥基類固醇脫氫酶3α抗體

Anti-HEC1抗體,癌細胞高表達蛋白Hec1抗體
Anti-HURP抗體,肝癌上調蛋白抗體
Anti-HOXD10抗體,同源盒蛋白HOXD10抗體
Anti-H5N1 Hemagglutinin抗體,A型流感病毒H5N1凝集素抗體
Anti-HPV16-E7抗體,人類乳頭狀瘤病毒16-E7抗體
Anti-H Cadherin抗體,心臟鈣粘蛋白抗體
Anti-HEPACAM抗體,肝細胞粘附分子抗體
Anti-Hyaluronidase2抗體,透明質酸酶2/*2抗體
Anti-Hyaluronidase3抗體,透明質酸酶3/*3抗體
Anti-HIF3 alpha抗體,缺氧誘導因子3α/HIF-3α抗體
Anti-HIFPH4抗體,缺氧誘導因子脯氨酰4羥化酶抗體
Anti-RBMX/hnRNP G抗體,糖蛋白P43抗體
Anti-HSP40抗體,熱休克蛋白家族40抗體
Anti-HACE1抗體,E3泛素蛋白連接酶HACE1抗體
Anti-HRASLS2抗體,HRAS樣抑制因子2抗體
Anti-HELLS抗體,淋巴特異性解旋酶抗體
Anti-HPRG抗體,*富含*糖蛋白抗體
Anti-Hemopexin抗體,糖蛋白β-1B抗體
Anti-HLTF抗體,解旋酶樣轉錄因子抗體